NHLBI Program Project Applications (P01 Clinical Trials Optional) — PAR-24-065

National Heart, Lung, and Blood Institute (NHLBI), NIH

NHLBI's multi-project program grant, and the institute's main route for assembling a team around a single problem: a minimum of three interrelated research projects plus optional administrative and scientific cores. The NOFO explicitly names implementation science, health disparities and translation research as within scope alongside basic and clinical work, which is where social work fits — a P01 on heart, lung, blood or sleep conditions can carry a behavioural or community-delivered project, an implementation project, and a disparities project under one roof. Budgets are large enough to fund

Indicative award

$1.5M–$1.8M per year (per year)Standard cap is $1,515,000 in direct costs per year. That rises to $1,765,000 per year when the application includes four or more projects with an Early Stage Investigator leading one of them, in which case a minimum of $250,000 must be directed to the ESI-led project. Maximum project period 5 years

Timing

Several times a yearSeveral times a year · Jan, May, SepNo specific published date recorded. This funder publishes a cycle rather than a date, and this database does not invent one.Three receipt cycles a year, on or about January 25, May 25 and September 25. The dated cycles published in the NOFO's Key Dates table run through September 25, 2025, and the NOFO expiration date is September 26, 2026 — so confirm the current 2026 receipt dates with NHLBI or the live NOFO page rathe

Who can apply

Mid-career & senior, Any faculty rank

Eligibility

Higher education institutions, nonprofits with 501(c)(3) status, for-profits, small businesses, and state, local and tribal governments may apply. Foreign organizations cannot apply directly, though U.S. organizations may include non-domestic components (which must obtain an NCAGE rather than a CAGE code). This is a team mechanism — a single investigator cannot apply, and at least three interrelated projects are required, so a social work researcher typically enters as a project leader or core director on an institutional application rather than as the overall PI.

SSWR clusters

Topics

implementation science · health disparities · cardiovascular health · sleep · team science

Apply at

https://grants.nih.gov/grants/guide/pa-files/PAR-24-065.html

This entry

Curated by the working group. Written 2026-08-07. Funder link last confirmed to resolve on 2026-09-25.

Amounts and dates on this page are indicative and are maintained by people rather than scraped. Funders change ceilings, windows and eligibility without notice; confirm all details at the source above before applying.

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NHLBI Program Project Applications (P01 Clinical Trials Optional) — PAR-24-065

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