Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required) — PAR-25-268
National Center for Complementary and Integrative Health (NCCIH), NIH
An R01 for fully remote efficacy or effectiveness trials of complementary and integrative interventions, with a strict design constraint: there must be no in-person contact at all between research staff and participants. Everything — recruitment, consent, delivery, assessment, retention — happens at a distance or through mobile health tools. That constraint is the point, because it tests whether these interventions can reach people who cannot get to a clinic: rural residents, unpaid caregivers, people with disabilities or transport barriers, and people whose work hours make in-person research
- Indicative award
- Amount not published (varies by call)No budget cap. The NOFO states that application budgets are not limited but need to reflect the actual needs of the proposed project. Maximum project period is 5 years.
- Timing
- Several times a yearSeveral times a year · Feb, Jun, OctPublished deadline: 2026-10-20 — 67 days awayThree cycles a year; published receipt dates include February 20, 2026, June 22, 2026 and October 20, 2026. A September 2025 correction notice (NOT-AT-25-008) adjusted key dates, so confirm against the current NOFO page before submitting. Expiration date is November 18, 2026.
- Who can apply
- Early-career faculty, Mid-career & senior, Any faculty rank
- Eligibility
- Domestic applicants only: non-domestic (non-U.S.) entities are not eligible, and non-U.S. components of U.S. organizations are also ineligible. Foreign collaborators, consultants and components are permitted, but clinical trial sites outside the U.S. or Canada are not. Eligible U.S. organizations include higher education institutions, nonprofits, for-profits, and government and tribal entities. A clinical trial is required — this is not a mechanism for observational or purely qualitative work.
- SSWR clusters
- Topics
- remote delivery · mhealth · telehealth · clinical trials · access to care
- Apply at
- https://grants.nih.gov/grants/guide/pa-files/PAR-25-268.html
- This entry
- Curated by the working group. Written 2026-08-07. The funder link has not yet been machine-checked.
Amounts and dates on this page are indicative and are maintained by people rather than scraped. Funders change ceilings, windows and eligibility without notice; confirm all details at the source above before applying.
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