Improving Methods for Conducting Patient-Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement — Cycle 3 2026
Patient-Centered Outcomes Research Institute (PCORI)
Funds methods studies addressing named gaps in patient-centered CER: patient-centered measurement, use of real-world data in multi-site studies, artificial intelligence and machine learning in CER, and study design.
- Indicative award
- up to $750k (total award)$12 million available in total; individual applications may request direct costs up to $750,000 over up to three years. No minimum published.
- Timing
- Several times a yearSeveral times a year · Jan, May, SepPublished deadline: 2026-09-09 — 26 days awayPFA opened Aug. 4, 2026. LOI deadline Sept. 9, 2026, 5 pm ET; LOI status Oct. 14, 2026; invited application deadline Jan. 12, 2027, 5 pm ET; merit review March 2027; awards announced August 2027; earliest start December 2027.
- Who can apply
- Any faculty rank, Mid-career & senior, Early-career faculty, Postdoctoral
- Eligibility
- Organisation-submitted; accepted LOI and PCORI invitation required before a full application. Projects must fall within the four named methodological priority areas. Applicants invited to submit may defer their application once to the immediately following cycle. Note PCORI does not fund research aimed primarily at developing and validating an instrument outside these methods priorities.
- SSWR clusters
- Topics
- research methods · patient-centered measurement · real-world data · ai and machine learning in research · study design
- Apply at
- https://www.pcori.org/funding-opportunities/announcement/improving-methods-conducting-patient-centered-comparative-clinical-effectiveness-research-pcori-funding-announcement-cycle-3-2026
- This entry
- Curated by the working group. Written 2026-08-07. The funder link has not yet been machine-checked.
Amounts and dates on this page are indicative and are maintained by people rather than scraped. Funders change ceilings, windows and eligibility without notice; confirm all details at the source above before applying.
Also on the Research Design and Measurement shelf
- Research Project Grant (R01)National Institutes of Healthup to $250k per year · Several times a year · Feb, Jun, Oct
- Exploratory/Developmental Research Grant (R21)National Institutes of Healthup to $275k · Several times a year · Feb, Jun, Oct
- Pathway to Independence Award (K99/R00)National Institutes of HealthAmount not published · Several times a year · Feb, Jun, Oct
- Doctoral Dissertation Research Improvement Grants (DDRIG)National Science Foundationup to $50k · Varies by programme
- Sociology ProgramNational Science Foundation$100k–$500k · Rolling / open
- William T. Grant Scholars ProgramWilliam T. Grant Foundation$350k · Annual cycle · Jul