Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 Clinical Trial Required)

National Institute of Mental Health (NIMH), National Institutes of Health

Hybrid trials that test the effectiveness of a mental health intervention and an implementation strategy at the same time, in community, school, online, or routine care settings, including mechanisms of action.

Indicative award

Amount not published (varies by call)Budgets are not limited but must reflect actual project needs. NIMH states it intends to commit $27,000,000 in FY 2026 across this NOFO and its companion opportunities; no per-award figure is published.

Timing

Several times a yearSeveral times a year · Feb, Jun, OctPublished deadline: 2026-10-15 — 17 days awayThree cycles a year (mid-February, mid-June, mid-October) through October 15, 2027; NOFO expires October 16, 2027.

Who can apply

Early-career faculty, Mid-career & senior, Any faculty rank, Community organisation

Eligibility

Higher education institutions, nonprofits, for-profits, state/local/tribal governments, school districts, faith-based organizations and non-domestic entities. A clinical trial is required, so applicants need a delivery-setting partner.

SSWR clusters

Topics

implementation science · hybrid trial · intervention effectiveness · community and school settings

Apply at

https://grants.nih.gov/grants/guide/pa-files/PAR-25-177.html

This entry

Curated by the working group. Written 2026-08-07. Funder link last confirmed to resolve on 2026-09-25.

Amounts and dates on this page are indicative and are maintained by people rather than scraped. Funders change ceilings, windows and eligibility without notice; confirm all details at the source above before applying.

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Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 Clinical Trial Required)

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