Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 Clinical Trial Required)
National Institute of Mental Health (NIMH), National Institutes of Health
Hybrid trials that test the effectiveness of a mental health intervention and an implementation strategy at the same time, in community, school, online, or routine care settings, including mechanisms of action.
- Indicative award
- Amount not published (varies by call)Budgets are not limited but must reflect actual project needs. NIMH states it intends to commit $27,000,000 in FY 2026 across this NOFO and its companion opportunities; no per-award figure is published.
- Timing
- Several times a yearSeveral times a year · Feb, Jun, OctPublished deadline: 2026-10-15 — 62 days awayThree cycles a year (mid-February, mid-June, mid-October) through October 15, 2027; NOFO expires October 16, 2027.
- Who can apply
- Early-career faculty, Mid-career & senior, Any faculty rank, Community organisation
- Eligibility
- Higher education institutions, nonprofits, for-profits, state/local/tribal governments, school districts, faith-based organizations and non-domestic entities. A clinical trial is required, so applicants need a delivery-setting partner.
- SSWR clusters
- Topics
- implementation science · hybrid trial · intervention effectiveness · community and school settings
- Apply at
- https://grants.nih.gov/grants/guide/pa-files/PAR-25-177.html
- This entry
- Curated by the working group. Written 2026-08-07. The funder link has not yet been machine-checked.
Amounts and dates on this page are indicative and are maintained by people rather than scraped. Funders change ceilings, windows and eligibility without notice; confirm all details at the source above before applying.
Also on the Mental Health shelf
- Research Project Grant (R01)National Institutes of Healthup to $250k per year · Several times a year · Feb, Jun, Oct
- Exploratory/Developmental Research Grant (R21)National Institutes of Healthup to $275k · Several times a year · Feb, Jun, Oct
- Ruth L. Kirschstein Predoctoral Individual NRSA (F31)National Institutes of HealthAmount not published · Several times a year · Apr, Aug, Dec
- Mentored Research Scientist Development Award (K01)National Institutes of HealthAmount not published · Several times a year · Feb, Jun, Oct
- Pathway to Independence Award (K99/R00)National Institutes of HealthAmount not published · Several times a year · Feb, Jun, Oct
- Behavioral health services and evaluation grantsSubstance Abuse and Mental Health Services Administration$100k–$5M · Periodic calls