Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)
National Institute of Mental Health (NIMH), National Institutes of Health
Two-phase trials of system-level interventions that change how mental health services are organised, financed, coordinated or delivered, with a feasibility R61 phase preceding an effectiveness R33 phase.
- Indicative award
- Amount not published (varies by call)Budgets are not limited but must reflect actual project needs. NIMH cites $27,000,000 for FY 2026 across this and companion NOFOs; no per-award figure is published.
- Timing
- Several times a yearSeveral times a year · Feb, Jun, OctPublished deadline: 2026-10-15 — 61 days awayThree cycles per year; listed dates run through June 15, 2027 and the NOFO expires October 16, 2027. R61 phase up to 2 years, R33 up to 4, 5 years combined maximum.
- Who can apply
- Mid-career & senior, Any faculty rank, Early-career faculty, Community organisation
- Eligibility
- Higher education institutions, nonprofits with or without 501(c)(3) status, for-profits and small businesses, state/local/tribal governments, school districts, community- and faith-based organizations, and non-domestic entities. Requires a clinical trial in a real service system.
- SSWR clusters
- Topics
- system-level intervention · service delivery · care coordination · policy and financing
- Apply at
- https://grants.nih.gov/grants/guide/pa-files/PAR-25-285.html
- This entry
- Curated by the working group. Written 2026-08-07. The funder link has not yet been machine-checked.
Amounts and dates on this page are indicative and are maintained by people rather than scraped. Funders change ceilings, windows and eligibility without notice; confirm all details at the source above before applying.
Also on the Mental Health shelf
- Research Project Grant (R01)National Institutes of Healthup to $250k per year · Several times a year · Feb, Jun, Oct
- Exploratory/Developmental Research Grant (R21)National Institutes of Healthup to $275k · Several times a year · Feb, Jun, Oct
- Ruth L. Kirschstein Predoctoral Individual NRSA (F31)National Institutes of HealthAmount not published · Several times a year · Apr, Aug, Dec
- Mentored Research Scientist Development Award (K01)National Institutes of HealthAmount not published · Several times a year · Feb, Jun, Oct
- Pathway to Independence Award (K99/R00)National Institutes of HealthAmount not published · Several times a year · Feb, Jun, Oct
- Behavioral health services and evaluation grantsSubstance Abuse and Mental Health Services Administration$100k–$5M · Periodic calls