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Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required)

National Institute of Mental Health (NIMH), National Institutes of Health

Development and early testing of novel psychosocial therapeutic and preventive interventions, with emphasis on demonstrating that the intervention moves a defined mechanism linked to mental disorder risk or maintenance.

Indicative award
Amount not published (varies by call)Budgets are not limited but must reflect actual project needs. NIMH cites $27,000,000 for FY 2026 across this and companion NOFOs; no per-award figure is published.
Timing
Several times a yearSeveral times a year · Feb, Jun, OctPublished deadline: 2026-10-15 — 62 days awayThree cycles a year through October 15, 2027; NOFO expires October 16, 2027. R61 phase up to 2 years plus R33 phase up to 3 years.
Who can apply
Early-career faculty, Mid-career & senior, Any faculty rank
Eligibility
Higher education institutions, nonprofits, for-profits, local/state/federal governments, independent school districts, faith-based organizations and non-domestic entities. A clinical trial is required and the intervention target or strategy must be novel.
SSWR clusters
Topics
psychosocial intervention development · prevention · mechanisms of change · experimental therapeutics
Apply at
https://grants.nih.gov/grants/guide/pa-files/PAR-25-182.html
This entry
Curated by the working group. Written 2026-08-07. The funder link has not yet been machine-checked.

Amounts and dates on this page are indicative and are maintained by people rather than scraped. Funders change ceilings, windows and eligibility without notice; confirm all details at the source above before applying.

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